The Manila Times

Immatics Announces Full Year 2025 Financial Results and Business Update

PRAME Cell Therapy: Global, randomized, controlled Phase 3 trial, SUPRAME, in previously treated advanced melanoma ongoing; anzu-cel received Orphan Drug Designation from the FDA for the treatment of ...

uniQure: Worst Case Scenario Becomes Reality

Qure’s AMT-130 faces FDA efficacy doubts after 12-month data. QURE's upside now hinges on political pressure. Read here for ...
BMJ Open

Speech-to-Speech Voice-Cloning Care (SVCC) for improving ICU-acquired anxiety for critically ill patients in a tertiary hospital in Beijing, China: protocol of a randomised ...

Introduction Intensive care unit (ICU) visiting restrictions in hospitals, implemented due to infection control and other factors, limited contact between patients and family members, affecting ...
STAT

I tried to design a clinical trial for a supplement. 5 things got in the way

When Elise Felicione tried to design a clinical trial for a supplement, 5 things got in the way. It’s a lesson for the ...
IPM

Randomized control trial shows drinking water promotion can prevent overweight and reduce sugar-sweetened beverage intake in schoolchildren

A new study in the American Journal of Preventive Medicine reports findings from a randomized controlled trial—the gold standard study design in health research—showing that promoting drinking water ...
FierceBiotech

FDA steers cancer CAR-T developers toward randomized superiority trials in policy shift

The FDA is raising the bar for approval of CAR T-cell therapies in oncology. Under plans outlined by the FDA’s biologics chief Vinay Prasad, M.D., the agency will require developers of many CAR-Ts to ...
IEEE

Safety-Critical Randomized Event-Triggered Learning of Gaussian Process With Applications to Data-Driven Predictive Control

Abstract: Safety and data efficiency are important concerns in data-driven control, especially for nonlinear systems with unknown dynamics and subject to disturbances. In this work, we consider a ...
Frontiers

The efficacy and safety of low-intensity focused ultrasound pulses for prolonged disorders of consciousness: a study protocol for a randomized controlled trial

Recent randomized controlled trials (RCTs) in patients with prolonged disorders of consciousness (pDoC) have yielded limited success. Among them, only studies involving amantadine have provided Class ...
law.uchicago.edu

Inaugural Ephraim Lecture Explores the Lessons of Randomized Controlled Trials

What policies and programs can society implement to make a tangible, lasting impact on people’s lives? Social scientists have been trying to answer this question for decades by conducting randomized ...
SciELO

Schizophrenia TreAtment with electRic Transcranial Stimulation (STARTS): design, rationale and objectives of a randomized, double-blinded, sham-controlled trial

Introduction Schizophrenia is a severe mental disorder. While some antipsychotic medications have demonstrated efficacy in treating positive symptoms, there is no widely recognized treatment for ...
The New England Journal of Medicine

A Randomized Trial of Shunting for Idiopathic Normal-Pressure Hydrocephalus

Idiopathic normal-pressure hydrocephalus is a neurologic disorder characterized by impaired gait, balance, cognition, and bladder control in older adults. The disorder is treated with shunt surgery, ...
Science-Based Medicine

Ivermectin to Control Malaria — A Cluster-Randomized Trial

Malaria causes about 1/4 billion new cases of disease and about 600,000 deaths every year. 3/4 of the deaths are children under 5 years old. The July 23, 2025, NEJM has a free full text article ...