We examine emerging consensus points for five key components of microarray analysis — design, preprocessing, inference, classification and validation. Biological replication is important in the design ...

Reviewed by Dr. Tomislav Meštrović, MD, Ph.D. The microarray is a recently developed technology used in cancer research and in the pharmacological treatment of other diseases such as oral lesions. In ...

Expert Rev Mol Diagn. 2013;13(6):601-611. In other situations, normal microarray analysis in the presence of an abnormal karyotype, such as marker chromosomes, is reassuring, as it indicates that the ...

The first study of the use of microarray patches to vaccinate children has shown that the method is safe and induces strong immune responses. The phase 1/2 randomized trial compared results from the ...

Genetic abnormalities have been associated with 6 to 13% of stillbirths, but the true prevalence may be higher. Unlike karyotype analysis, microarray analysis does not require live cells, and it ...

Although the superiority of expression-based biomarkers, as compared with traditional clinical staging, has been disputed, 33 a nationwide clinical trial is under way in the Netherlands in which ...

Reviewed by Dr. Tomislav Meštrović, MD, Ph.D. Microarray or biochip is a lab-oriented microscope slide that is usually made of glass, silicon chip, or nylon membrane. It is a 2D array (sometimes 3D) ...

A survey of scientists developing bioprocesses found efficiency to be the top concern, with pressure growing each year to “produce more, do it more quickly, and do so with fewer resources.” 1 Yet, ...

Scientists at the Leibniz Institute of Photonic Technology (Leibniz IPHT) have developed a new microarray-based diagnostic platform that can help close vaccination gaps and quickly detect ...

Genetic research labs are under constant pressure to increase their throughput while bringing down costs. Even though emerging new technologies can help labs expand their analysis capabilities, it’s ...